Atrophy of one side of the papilla and edema of the other side are usually seen in tumors or abscesses at the base of the frontal lobe of the brain, such as internal carotid artery aneurysms, olfactory groove meningiomas, meningiomas at the base of the skull in the anterior cranial recess, and craniopharyngioma. Other tumors such as internal carotid artery spindle dilation, internal carotid artery sclerosis, trauma to the anterior cranial sulcus, arachnoiditis of the anterior cranial sulcus may also cause atrophy of the optic papilla on one side and edema on the other side. As one side of the optic nerve is directly compressed by the tumor and atrophied first, later on the tumor continues to grow and increases the intracranial pressure, resulting in edema of the healthy side of the optic papilla. How to diagnose atrophy of one side of the papilla and edema of the other side? Through fundus examination, if the optic papilla of one eye is pale or pale and atrophied, while the optic papilla of the other eye is elevated with blurred edges and edema, it means one side of the papilla is atrophied and the other side is edema. Psychiatric symptoms can be seen in other parts of the skull, but those caused by frontal lobe tumors are more prominent and appear earlier, and the incidence is higher, especially when both frontal lobes are damaged, the psychiatric symptoms of frontal lobe tumors are mainly manifested as memory impairment and personality changes, which are more common in frontal lobe anterior and frontal lobe base tumors. With the gradual development of the disease, the thinking and synthesis ability is obviously lost, both distant and near memory gradually disappears, loss of self-knowledge and judgment, disorientation to time and place, patients gradually become demented, personality changes are also very common, mainly manifested as intelligence disorder, indifferent expression, indifferent to surrounding things, not knowing Some patients show loss of inhibition, agitation, irritability, euphoria, wit, childish behavior, child-like dementia, frivolity, stupidity, annoying jokes, and even strong crying and laughing, sometimes showing passionate and even rage attacks, such as hair erection, blood pressure rise, pupils dilated and accompanied by aggressive movements. The incidence of mental symptoms of frontal lobe tumor is generally around 60%, and mental symptoms can occur in all parts of the skull at a certain stage of disease development. In addition to lesions in all lobes of the cerebral hemisphere, subcurtain lesions and patients with increased cranial pressure can also appear, therefore, the diagnosis of frontal lobe tumor is not enough based on mental symptoms alone. Gliomas are rare, mostly meningocele. In addition to the common symptoms of increased cranial pressure, patients often have localized signs, such as olfactory disturbance, visual impairment, visual field defects, optic nerve atrophy on the diseased side, and edema of the contralateral optic papilla, called foster-kennedy syndrome.