There are many dangers of gout, statistics say that gout patients “gouty nephropathy – clinical 20%-40%, autopsy 100%” afraid. Gout to be visible to the naked eye gout stone, chronic gouty nephropathy or X-ray visible joint destruction before starting uric acid treatment is late, in order to avoid kidney function damage, joints and other serious damage, regular treatment and diet is still needed. Hyperuricemia is increasing in adults, with a proportion of about 10% in people over 30 years old, and some may be higher. Gout acute attack Control acute inflammation (treat its symptoms first) NSAIDs: generally have a very obvious effect (aspirin is prohibited) Colchicine: 0.5mg/tablet, 1/h until relief or GI symptoms (nausea vomiting diarrhea), max 20ml/min), no kidney stones, urine urine <600mg/d (3571 μmol/d) Precautions: Drink plenty of water/ Alkaline drugs (100-fold increase in solubility at urine PH8), thiazide diuretics/aspirin/alcohol are prohibited. The third class of drugs for gout: drugs that promote uric acid catabolism include rasburicase and pegloticase, which are also being studied and progressed. Clinically, the selection of "two birds with one stone" should be advocated according to the disease that the gout patient is suffering from. Gout patients with hypertension can choose coxsartan or amlodipine, and domestic and international studies have confirmed that coxsartan has both uric acid-lowering and antihypertensive effects. Gout patients with hyperlipidemia can choose fenofibrate or atorvastatin. The former is suitable for those with mainly increased triglycerides, while the latter is suitable for those with mainly increased cholesterol. Fenofibrate 200 mg/d for 3 weeks or 160 mg/d for 2 months can reduce blood uric acid by 19% and 23%, respectively [P2-23]. Fenofibrate also has some anti-inflammatory properties and is less likely to induce acute attacks of gout when lowering uric acid.