Since 1999, our department has been the first to carry out multi-electrode radiofrequency ablation of liver cancer in East China. After years of exploration and conclusion, we are now able to carry out local ablation of liver cancer in many ways, and can deal with liver cancer in various special areas, including almost all ablation techniques, with a full range of treatment means, expanding the space for comprehensive treatment of liver cancer, and adding a powerful weapon for patients to fight and prolong their survival. . The ablation techniques for hepatocellular carcinoma in various cases are introduced as follows. 1. Percutaneous liver puncture ablation technique: This is the conventional liver cancer ablation technique and the most carried out treatment means, which is suitable for liver cancer lesions with safer puncture path and not affected by surrounding conditions. The picture below shows an 81-year-old male patient who underwent interventional embolization of liver cancer in December 2012 and multi-electrode radiofrequency ablation in May 2013, with AFP reduced from 15,400u to 4u, and is now living a normal life. 2. Open hepatic puncture ablation technique: under open conditions, the peripheral organs can be isolated from thermal injury; it can deal with some special sites where percutaneous hepatic puncture cannot be put in place. This approach is suitable for patients with poor liver function reserve that cannot tolerate surgical resection. Case 2.1 is a special site of hepatocellular carcinoma where percutaneous hepatic puncture is not operable. Case 2.2 is tumor adhesion to colon and liver flexure, which needs to be separated to avoid damage.3. Laparoscopic percutaneous liver puncture ablation technique: Under laparoscopy, the peripheral organs are freed to expose the liver cancer lesions on the dirty surface and percutaneous liver puncture ablation is performed. This approach avoids the need for surgical incision and is particularly useful in cases where the patient is considering a next walk liver transplant to avoid causing intra-abdominal adhesions that could interfere with the liver transplantation procedure. Case 3.1 is a small hepatocellular carcinoma for which laparoscopic microwave ablation was chosen in preparation for liver transplantation. Case 3.2 is a multiple lesion, where two lesions within the liver parenchyma were first ablated by percutaneous liver puncture, followed by laparoscopic treatment of the lesion close to the intestinal canal. 5.Percutaneous liver puncture portal vein cancer thrombus ablation technique: percutaneous puncture into the portal vein, soft electrode into the portal vein cancer thrombus site, and RF ablation after imaging confirmation, while injecting chemotherapeutic drugs, or iodine oil. Radiofrequency ablation of portal vein cancer thrombus with soft electrode operated under DSA