Swelling of woman’s calves may be due to physiological edema caused by standing or sitting for too long, but also can be seen in premenstrual tension syndrome, hypothyroidism, edema in pregnancy, cardiac insufficiency and renal insufficiency and other conditions. 1. Physiological edema: Swelling of the calves can occur when sitting or standing for a long time, which can be relieved by resting and elevating the legs. 2. Premenstrual tension syndrome: women of childbearing age may have edema of the eyelids and lower limbs 7~14 days before the onset of menstruation, the cause of which may be related to changes in endocrine hormones. 3. Hypothyroidism: Prevalent in females, it may present with non-sunken edema of the lower legs, accompanied by symptoms such as fatigue, obesity, alopecia, and depressed mood. 4. Edema in pregnancy: most women will have different degrees of edema in the late stage of pregnancy, most of which are physiological edema. Some of them are pathologic edema, which needs further examination and timely treatment. 5. Cardiac insufficiency, renal insufficiency: can lead to female patients with calf swelling, and can be accompanied by shortness of breath, foam in the urine, oliguria and other symptoms. There are many possible causes of calf swelling in women, so they should consult a doctor in time to improve the examination and combine with medical history and other symptoms, so that the doctor can make a clear diagnosis and actively treat the disease.