Patients with advanced hepatocellular carcinoma should mainly have a liquid diet because the late stage of liver tumor is easy to be complicated by portal hypertension or esophagogastric fundic varices, which are also easy to cause bleeding, so soft food should be the main focus. Attention should be paid to increase high protein food, including fresh meat, such as beef, mutton, fish and seafood. Because the advanced stage of liver malignancy will show obvious anemia and hypoproteinemia, after exogenous supplementation can improve these symptoms. Also, attention can be paid to supplementation of vegetable proteins as well as fresh fruit juices, vitamin-rich foods, and if necessary, intravenous nutritional support or supplementation of suspended red blood cells as well as plasma, human albumin and other nutrients through peripheral veins, mainly to alleviate the patient’s pain.