Technological innovations in the field of medical devices can bring fundamental changes to healthcare. Recently, a foreign report based on the current state of the medical market from 2009 to 2014 listed 10 new medical technologies with great growth potential, whose market valuation reached 454.3 billion U.S. dollars. A large number of revolutionary technological innovation to the medical field has brought about new changes. 1. Diagnostic imaging and pain relief. Representative: capsule endoscopy. A report shows that 2/5 (about 177.8 billion U.S. dollars) of the market share of the top ten new medical technologies comes from internal medicine diagnostic technology, including nuclear medicine imaging, interventional radiology, and capsule endoscopy. The report released by the U.S. Frost & Sullivan consulting firm shows that in the past decade, medical imaging technology will shorten the imaging time to a few seconds, to take out the image is three-dimensional, full-color, and can largely replace the past puncture biopsy. For example, nuclear medicine imaging technology for non-invasive examination of liver fibrosis to lay the foundation; capsule endoscopy to save patients from pain. The capsule gastroscope is slightly larger than a regular capsule and has a camera the size of a grain of rice. When swallowed, it takes pictures at a rate of two per second and sends them in real time to an in vitro image recorder, which is expelled with the bowels six to eight hours later. Doctors only need to analyze the collected photos to get a glimpse of the condition of the gastrointestinal tract. Capsule gastroscopy has even made it possible to check at home and then send the photos to the doctor using a cell phone or computer, which may lead to early detection of gastric cancer, among other things. But it also has drawbacks, such as the 50,000 photos taken in 8 hours, 70% to 80% are of no diagnostic value, and there are blind spots. These problems need to be solved by cooperation between manufacturers and doctors. 2.Molecular diagnosis to locate cancer. Representative: molecular targeted therapy. The top scientific journal Nature? Genetics” as early as a few years ago, molecular diagnostic technology as the top ten health technology. It plays a huge role in the prevention, diagnosis and individualized treatment of genetic diseases, infectious diseases and tumors. Taking tumors as an example, the Global Cancer Report 2014 released by WHO pointed out that in 2012, the number of cancer deaths in China was 2.2 million, accounting for 26.8% of the global total, and the treatment effect of China’s tumor patients is still unsatisfactory. The solution lies in improving the early diagnosis rate and precise treatment for advanced tumors. About 80% of lung cancer patients are already in advanced stages when they are diagnosed, losing the chance of surgery. Traditional chemotherapy is a “trial-and-error treatment”, in which a chemotherapy regimen is chosen according to the guidelines, and the efficacy is evaluated after 2 cycles of treatment; if it is effective, the original regimen will be continued, and if it is not effective, the regimen will be changed. This model has poor efficacy and high side effects. Studies have shown that tumor development is often associated with genetic abnormalities, such as lung cancer, especially lung adenocarcinoma, which often has specific driver genes. To identify the driver gene, molecular diagnosis is needed to help. Finding specific genes and giving targeted molecular targeted therapy is effective and has fewer side effects. For example, for advanced lung cancer patients carrying EGFR-sensitive mutation genes, EGFR-TKI (e.g., gefitinib, erlotinib, etc.) targeted therapy can achieve a disease control rate of up to 90%, with no need for hospitalization and a high quality of life. As a result, many pharmaceutical companies have devoted themselves to this field, and the molecular diagnostic market is growing at an annual rate of 15% to 18%. 3.Minimally invasive technology to reduce the wound. Representative: minimally invasive internal fixation. In 1987, French doctor Murray completed the world’s first laparoscopic cholecystectomy, creating a new era of minimally invasive surgery. Over the decades, from gastroenteroscopy to laparoscopy, the concept of minimally invasive has penetrated into various medical fields. Some foreign scholars refer to minimally invasive surgery, genetic engineering, and organ transplantation as the three main streams of medical development in the 21st century. 4.Drug delivery system, on-demand drug delivery. Representative: nanocrystal technology. Foreign reports show that drugs with drug delivery system (DDS) have occupied a market share of about 110.8 billion U.S. dollars.Early research on DDS focused on slow and controlled release formulations, allowing patients to take a shot to maintain a longer period of time. For example, leuprolide acetate microspheres, treprostinil microspheres, and risperidone microspheres are widely used in the treatment of tumors, metabolic diseases, and psychiatric disorders. In recent years, the main goal of DDS research is to make up for the bioavailability defects caused by the chemical structure of the drug itself. For example, the intestinal retention technology developed by the American AvMax company enables the drug to stay in the small intestine, where the bioavailability is optimal, to maintain its effect on Helicobacter pylori and treat peptic ulcer. The nanocrystalline drug delivery technology of Elan contains an excipient that prevents aggregation and improves dissolution, solving the problem of time-dependent drug delivery, synchronizing drug delivery with the body’s rhythms, and maintaining a balanced blood level 24 hours a day, which has been effective in the treatment of high blood pressure. Recently, Stephen of the Massachusetts Institute of Technology? Morton developed a dual-drug, time-delayed nano-delivery system for the treatment of cancer, which prevents cancer cells from becoming resistant to chemotherapeutic drugs. It can be seen that nanotechnology is an important direction for the development of DDS. 5.Non invasive testing, instead of puncture. Representative: saliva detection of blood sugar. Blood, amniotic fluid, bone marrow …… indicators of these fluids are the basis for diagnosis of many diseases. But access to them requires puncture, invasive, not only bring pain to the patient, but also easy to cross-infection. Like diabetic patients are more in need of uninterrupted blood glucose monitoring and poor treatment compliance. The development of non-invasive testing devices based on biosensor technology brings hope to patients. According to the American Physicist Organization Network reported in 2012, the United States Purdue University scientists invented a sensor that can detect diabetes through tears and saliva, but also diagnose Parkinson’s disease and Alzheimer’s disease. Mary K. Norton, associate chair of the Department of Clinical and Translational Genetics at the University of California, San Francisco, has developed a non-invasive sensor to detect diabetes through tears and saliva. Dr. Norton, on the other hand, has developed non-invasive prenatal testing technology that can detect more than 80% of common chromosomal triploidy abnormalities (e.g., Down syndrome), and is expected to replace chorionic villus sampling and amniocentesis. With the development of wearable medicine, non-invasive testing technology is expected to enter thousands of households and realize 24/7 monitoring. For example, Israel’s BIG has developed a watch-type blood glucose monitoring device, which monitors the condition by measuring changes in bioelectrical resistance. But the U.S. science and technology magazine “collect the world” proposed, non-invasive blood glucose detection technology is still in the early stages of development, no products on the market. Liu Qingjun said, how to ensure that the data is more accurate, more reliable analysis, is the technical difficulties faced by such devices. 6, mobile medical, to ensure safety. Representative: hospital information technology. A U.S. doctor sitting in the office, you can view the Chinese patient’s ECG through a wearable device, which is a beautiful outlook brought by mobile medicine. The famous American cardiologist Eric? Topper listed it as the most promising new medical technology. The advantage of mHealth is that it is patient-centered, maximizing the quality and safety of medical care while improving efficiency. When giving infusion or issuing medicine, the nurse scans the barcode on the patient’s wristband and medicine with the mobile PDA, and if it matches, the word “successful” will pop up, otherwise, it will give the prompts such as “the patient does not match with the doctor’s prescription” and “the doctor’s prescription does not exist”, realizing the patient’s medical needs and the patient’s medical condition. Otherwise, it will give tips such as “the patient does not match the medical advice” and “the medical advice does not exist”, thus realizing zero error in the use of medication. According to a report published by the GSM Association, the development of the mHealth market in 2017 will bring in$23 billion in revenue. Mobile healthcare will play a role in chronic disease management and individualized medicine. 7, Microfluidic and microelectromechanical systems. 8.Biomaterials (including antimicrobial wound care technologies and orthopedic materials). 9, Bioactive implants, such as neurostimulation devices. 10, Telemedicine. Of these, about 2/5 ($177.8 billion) of the market share comes from internal medicine diagnostic technologies. Drug delivery devices also accounted for about$110.8 billion of market share. This report examines the healthcare market from March 2009 through March 2014. The fastest growing medical device segments include biomaterials, telemedicine technology, microelectromechanical systems, microfluidics, and mobility assistive technology. Of these, biomaterials have the strongest growth potential due to their large market share. As of 2009, the biomaterials market was valued at$46.6 billion. By 2014, the market is expected to increase to$85.5 billion. The biomaterials market for antimicrobial wound dressings is the fastest growing segment. in 2009, antimicrobial wound dressings were expected to reach$330 million. By 2014, it is expected to grow by$780 million. In the healthcare industry, the combination of medical devices and imaging technologies with IT is also generating significant growth.