Premature ovarian failure refers to the failure of female ovarian function, mostly endocrine-related, with complex and diverse symptoms, but mainly menstrual changes, low reproductive function, and some other accompanying symptoms. First, changes in menstruation. Menstrual disorders may occur, usually in the form of late menstruation, sporadic menstruation, and sudden amenorrhea in some patients. Premature ovarian failure is mainly due to low estrogen levels in the body, without estrogen support ovarian function is impaired, resulting in abnormal ovulation, so the abnormal changes in menstruation mentioned above. Second, low reproductive function for women is mainly prone to infertility. The key to female conception is ovarian ovulation. In premature ovarian failure, estrogen is low and ovarian function is low, resulting in sparse ovulation, which makes it difficult for women to conceive. Third, premature ovarian failure can also lead to some symptoms associated with low estrogen, such as low libido, reduced vaginal discharge, painful intercourse, hot flashes and night sweats. The most important thing is to pay attention to a healthy lifestyle, exercise and not to use hormonal drugs to prevent premature ovarian failure and to seek medical attention if the above symptoms occur.