Gout is a common disease that endangers human health. Proper understanding of the causes of gout, treatment principles and preventive measures will greatly improve the healing process and prolong the life of patients. 1.What is gout? The end product of metabolism of purines taken from food and purines synthesized in the body is uric acid, which is maintained at a certain level in the blood of normal people and excreted through the kidneys. Gout includes gouty arthritis, hyperuricemia, gout stone, gouty nephropathy, etc. Generally speaking, high-protein foods contain more purines. Throughout the ages, emperors, kings, scientific and religious leaders have suffered from gout, such as Alexander, Kublai, Newton, etc. All suffered from gout. Therefore, gout is also known as “emperor’s disease”, “disease of wealth”, “disease of wine and meat”, etc. With the improvement of living standards in modern society and changes in diet structure, the incidence of gout has greatly increased, especially in men over 40 years old and in men and women. Especially in men over 40 years old and postmenopausal women, the incidence is more common. 2, how to classify gout gout is divided into primary gout and secondary gout. Primary gout is mostly caused by enzyme defects in the body, the etiology of this type of gout treatment is very difficult, secondary gout is often due to kidney disease, tumor chemotherapy and other reasons, through the corresponding etiological treatment, can be a certain effect. The gouty arthritis is often characterized by the following features: (1) sudden acute inflammation of the joints: local redness, swelling, heat and pain. (2) Pain is severe and unbearable, often affecting sleep due to pain. (3) The joint is afraid of pressure and refuses to be pressed, and there is often localized debridement after the joint inflammation subsides. (4) The affected joints are asymmetrical, and the joints of the lower extremities are commonly involved, especially the first metatarsophalangeal joint of the foot is the most vulnerable, and 75% of patients have their first attack in this area. (5) In most cases, the acute inflammation of the joint resolves quickly, about 7-10 days, and often leaves no joint deformity. (6) The inter-episode period may be asymptomatic, but a small number of patients with chronic gout have prolonged, recurrent attacks with no obvious interval. These characteristics are often very different from rheumatoid arthritis and other joint diseases, the differential diagnosis is not difficult. 4, what is the purpose of treatment of gouty arthritis (1) rapid control of acute inflammation of the joints. (2) To prevent recurrence of arthritis. (3) To prevent or treat comorbidities caused by uric acid crystals deposited in joints, kidneys or soft tissues. 5.How to treat the acute phase of gouty arthritis (1) timely anti-inflammatory and pain relief: immediately apply non-hormonal anti-rheumatic drugs, such as Fotarine, Chironolactone, Asimexin, etc. Pay attention to only one kind of drug for short-term treatment according to the situation, and the drug can be stopped after the acute inflammation of the joint subsides. Although colchicine, which has been used for many years, has a good anti-inflammatory and pain-relieving effect, it has been replaced by the above-mentioned drugs in recent years due to many adverse reactions, so it is not used as the drug of choice. (2) Drink more water: more than 2,000 ml per day and take alkaline drugs in appropriate amount, such as heavy cao, to alkalize urine and promote uric acid excretion. (3) Strictly consume low purine diet and abstain from alcohol: low purine diet is mostly vegetarian, such as fruits and some vegetables, as well as eggs, milk and gummy foods, such as sea cucumber and hoof tendons. During acute arthritis, a high purine diet should be prohibited, such as various animal offal, seafood, broth, fish soup, beef, lentils, spinach, etc. You should also abstain from eating various fermented foods and abstain from alcohol, especially high concentrations of white wine and colored wine, such as wine and champagne, etc. Drinking alcohol can often trigger or aggravate gouty arthritis. 6, gouty arthritis interval how to treat this period of treatment has two objectives, namely to maintain the blood uric acid level in the normal range and prevent the onset of gouty arthritis. According to the following two different situations to deal with: (1) If the blood uric acid is not high or mildly elevated, and arthritis attacks are not frequent, in addition to dietary treatment, no treatment can be given. (2) If the blood uric acid is significantly elevated for a long period of time, and the arthritis is recurrent, accompanied by gout stones and kidney stones, etc., uric acid-depleting drugs, such as propoxur and allopurinol, can be given. The application of uric acid-removing drugs should overcome the arbitrariness, must be taken under the guidance of a doctor, should not be a variety of drugs at the same time, and the amount of drugs for the elderly should also be small, and should often check the blood picture, liver and kidney function, in order to observe the adverse drug reactions. Special attention should be paid to avoid taking uric acid removal drugs when the acute inflammation of the joints has not yet subsided, otherwise, it will aggravate the condition. In order to reduce the attack of gouty arthritis and lower the blood uric acid level, in addition to the above treatment, we should actively search for the cause of secondary gout and carry out long-term treatment for the cause in order to receive good results. There are also many related diseases that often exist in combination with gout, such as obesity, diabetes, hyperlipidemia, hypertension, etc. According to the literature, 78% of gout patients are over the standard weight, 75%-84% have hyperlipidemia, 0.1%-9% have diabetes, 25%-50% have hypertension, therefore, gout patients should control their weight within the standard range and actively treat hyperlipidemia, diabetes, hypertension, etc., which will be beneficial to prevent gout and reduce the disease. In conclusion, gout is not a stubborn disease, as long as the cause of the disease is carefully searched for, related diseases are prevented and treated, and active and effective drug and dietary treatment is carried out for different periods, the acute inflammation of the joints can be reduced and the deposition of uric acid salts in the organs can be reduced, thus alleviating the pain of patients and keeping the organs functioning well for a long time, which will certainly improve the quality of life of patients and prolong their life expectancy.