When it comes to popcorn, those who have consumed it will immediately think of its exotic appearance, juicy, sweet and sour. However, what many people do not know is that it can also cause trouble, bringing deliciousness to humans while also creating a lot of trouble. In the past few days, we have seen a seriously ill patient who was sent down from emergency care for treatment: Lao Hu, male, 66 years old, with a history of hypertension, started peritoneal dialysis treatment 1.5 years ago due to uremia. The patient was admitted to the hospital due to confusion. After admission, multiple test results could not explain the patient’s clinical manifestations, and then after repeatedly asking the family about the patient’s condition before the onset of the disease, we learned that the patient had eaten a popcorn of about 200g and then developed persistent erratic, and after more than 10 hours, his consciousness gradually became impaired and he was confused. After a joint consultation with emergency care physicians, abdominal dialysis physicians and hemodialysis physicians, the patient was considered to have a high probability of popcorn poisoning and was immediately treated with hemofiltration and hemoperfusion. After six consecutive intense treatments, Laohu finally opened his eyes and his consciousness gradually recovered. It seems that the cause of his coma was the popcorn. Is it really that harmful? Can’t uremic patients eat them? Poppy peaches (scientific name: Averrhoa carambola L.), alias: five convergence seeds, Yang peach, peach, three Lianzi, etc., is a tropical subtropical fruit, has a very high nutritional value. It is a tropical and subtropical fruit with high nutritional value. Healthy people often have no adverse effects after eating it. However, improper consumption or patients with kidney disease may suffer injuries or even life-threatening situations after consumption, Laohu is a typical example. In recent years, it has been reported in the literature at home and abroad. The main manifestations of poisoning after consuming popcorn are gastrointestinal symptoms, intractable eruption and neuropsychiatric abnormalities, hematuria, hyperkalemia, rapid deterioration of renal function, recurrence of previous renal disease, etc. Nero et al. summarized 32 patients, in which intractable eruption was the most common (accounting for 93.75%), followed by vomiting (68.7%), varying degrees of impaired consciousness (65.7%), weakness, numbness of the limbs ( (40.6%), epilepsy (21.8%), hypotension, shock (9.3%). And the popcorn poisoning was classified into 3 grades: mild: erratic, vomiting, insomnia. Moderate: irritability, abnormal sensation of limbs, mild impairment of consciousness. Severe: moderate or severe disturbance of consciousness, coma, seizures, hypotension, and shock. Patients with altered consciousness have a poor prognosis and high mortality rate. nero et al. concluded that peritoneal dialysis is ineffective for popcorn poisoning and that most patients recover after daily intensive hemodialysis treatment. neurological sequelae are uncommon in patients in remission after treatment. The pathogenesis has not been clarified, but it is speculated that it may be due to the presence of large amounts of irritating neurotoxins such as oxalate in poppy peaches and the possibility of causing a metabolic reaction in the organism. The nephrotoxicity of popcorn should be taken into account, not only for patients with renal insufficiency, but also for healthy adults and children, who should not consume too many popcorn at one time. In addition, patients with kidney disease, especially those with kidney failure, should avoid fruits and vegetables with high potassium content, such as bananas, oranges, potatoes, mushrooms, shiitake mushrooms, dark leafy vegetables, etc. Those with edema should avoid fruits with high water content, such as watermelon and cucumber. Beans also contain high levels of potassium and phosphorus and should be consumed less. Do not drink too thick fruit and vegetable juices, vegetable soups, and cook with boiling water and then stir-fry or mix with oil to make it light. Although after active resuscitation, Laohu turned to safety, but the tragic cost of 20 days of coma reminded us again: patients with kidney disease, please stay away from popcorn, remember.