Irritable bowel syndrome (IBS) is a clinical manifestation of habitual diarrhea. The disease is caused by the dysfunction of the “brain-gut axis” due to work stress and brain overwork, and office buildings and white-collar workers are most vulnerable to this disease. It is different from infectious diarrhea in that there are no viral bacteria in the stool examination; it is also different from colitis in that it does not cause the phenomenon of intestinal inflammation. The important symptoms of this disease are: diarrhea, frequent loose stools, often with a sense of emergency discharge of stool; constipation, difficult or reduced defecation; or alternating diarrhea and constipation. Diagnostic criteria: 1. The presence of epigastric pain, with symptoms of epigastric discomfort such as bloating, early satiety, belching, nausea, and vomiting, lasting at least four weeks or accumulated over twelve weeks in December. 2, Endoscopic examination did not reveal organic lesions such as gastric and duodenal ulcers, erosions, tumors, etc., no esophagitis was found, and there was no history of the above diseases. 3, laboratory, ultrasound and X-ray examinations to exclude hepatobiliary and pancreatic diseases; 4, no diabetes mellitus, renal disease, connective tissue disease and psychiatric disease; 5, no history of abdominal surgery. The selection of research cases should also exclude those with irritable bowel syndrome, so as not to affect the comparability of the study; no new organic lesions were found by regular follow-up for more than one year. Diagnostic procedure: FD is a diagnosis of exclusion, and in clinical practice, it is required not to miss organic disease, but not to conduct a comprehensive extra-laboratory and special examination for each case without selectivity. For this reason, on the basis of comprehensive history taking and physical examination, we should first determine whether the patient has the following “alarm symptoms and signs” of organic diseases: 45 years of age or older, recent onset of dyspepsia; wasting, anemia, vomiting blood, black stool, dysphagia, abdominal masses, jaundice, etc.; progressive worsening of dyspepsia symptoms. For those who have “alarm signs and symptoms”, a thorough examination must be conducted until the cause is found. For those who are 45 years old or older and do not have “alarming symptoms and signs”, basic tests such as blood, urine routine, fecal occult blood test, blood sedimentation, liver function test, gastroscopy, abdominal ultrasound (liver, gallbladder, pancreas) can be selected, or empirical treatment can be given for 2-4 weeks to observe the efficacy. Further examination should be selected for those with doubtful diagnosis or ineffective treatment.