Cranial repair surgery is very common in neurosurgical practice and is a very routine and classic procedure. In fact, thousands of years ago, our ancestors were practicing cranial repair surgery. After thousands of years of development and evolution, cranial repair surgical techniques have been continuously improved and have become very mature under modern medical conditions. Before cranial bone repair surgery, the selection of repair materials is very important. Currently, the most widely used material in clinical practice is titanium mesh, although this material has its progress compared to the earlier traditional materials. However, titanium mesh material still has its limitations and shortcomings, and is not very ideal, and there are problems in clinical application from time to time. For example, postoperative infection and rejection, skin abrasion and ulceration, exposure of the material, hot and cold sensitivity discomfort, affecting the CT MRI and so on. So, are there many cases of leakage of titanium steel in cranial repair? In fact, there is no lack of cases. For example, Ms. Peng from Jiangxi, she has been doing cranial repair with titanium mesh locally for eleven years, and recently found that there was a skin breakage in the forehead, which was prompted by the CT examination of the head that the titanium mesh was exposed, and the breakage place was getting bigger and bigger later on, which made her very anxious. The doctor suggested that he needed to remove the titanium mesh material as soon as possible and replace it with a better cranial repair material. After a lot of understanding, she came to us, our team after a detailed scientific diagnosis and evaluation, skull data collection, material 3D customization, PEEK plate delivery to the hospital, the team collaborated for Ms. Peng to complete the PEEK cranioplasty, a surgery to complete the removal of the titanium mesh material, the placement of the new PEEK material, which not only reduces the huge pain brought about by multiple surgeries, but also save a large portion of the operating costs for the patient. This not only reduces the pain caused by multiple surgeries, but also saves a large portion of the surgical costs for the patient. At the same time, the operation also carried out aesthetic plastic treatment of skin damage, and the patients were very satisfied after the operation. Therefore, titanium mesh material is not recommended to be used now, it is recommended to choose more advanced polyether ether ketone PEEK material for cranial bone repair, and it is also recommended to replace it with PEEK material if titanium steel leaks out of the cranial bone repair in the early stage or if there are other problems. We can replace the material in one surgery. And our team continues to carry out technological innovation and upgrading, material optimization and design, and the introduction of the concept of cosmetic plastic surgery, the PEEK cranial bone repair plastic surgery, in the clinic to achieve good results, but also gained the majority of patients and their families unanimously praised and highly recognized, around the many patients with cranial defects, including titanium leakage of the patient have come to the clinic in the name of the patient.