Epidermoid cysts are mainly eliminated by surgery. Epidermoid cyst is a slow-growing benign lesion, about 1% of cases have malignant tendency, can occur in all parts of the body, usually in the scalp, face, neck, trunk and buttocks, etc., the most common occurs in sebaceous overflow area, such as the head, face, forehead, back, located in the subcutaneous tissues or shallower. the incidence rate of 30 ~ 40 years old is higher, can be single or multiple, the average size is 5.2 cm. Epidermoid cysts are mostly asymptomatic, and those with small size or insignificant symptoms can be actively followed and observed; on the contrary, when the cysts are large and the symptoms are obvious, surgical excision is required. Surgery can also be considered when preoperative characterization is difficult. Epidermoid cysts should be completely removed during surgery to prevent the possibility of recurrence caused by residual. Patients with epidermoid cysts should go to the hospital in a timely manner and under the guidance of the doctor for regular treatment.