1.Drug and psychotherapy: For early lesions are mild, pancreatic spasm patients should explain the condition, stabilize emotion, eat less and more, chew slowly, and take sedative and antispasmodic drugs, such as calcium antagonist nifedipine, etc. can relieve symptoms. 2.Interventional dilation After placing the apical capsule catheter in the cardia, inject water, barium or mercury into the capsule to make the capsule expand, and then pull it out strongly so that the muscle fibers can be broken to expand the lumen of the narrowed lower esophagus, which requires repeated dilation. In a few patients, there is still a risk of complicating esophageal perforation. At present, lower esophageal dilatation is only suitable for early cases where surgery is contraindicated or refused and the esophagus is not yet highly enlarged. 3.Surgical myotomy: Traditional surgery is usually performed transthoracically, with long incisions and trauma, causing much pain to the patient. Nowadays, the surgery can be done under thoracoscopy or laparoscopy, and only three small incisions of 1-1.5 cm are needed on the chest wall or abdominal wall. The procedure performed in our center is laparoscopic. The main points of the procedure are: the muscle layer of the esophageal wall is incised longitudinally on the left side of the anterior exterior of the esophageal wall, reaching deep into the mucosa, but without cutting through the mucosal layer. The lower end of the incision crosses the gastroesophageal junction, and only 1 cm of the muscle layer of the gastric wall needs to be cut, and the upper end of the incision should be extended to the top of the enlarged hypertrophic segment of the esophageal wall, and the length of the incision varies depending on the lesion, and is generally about 5 to 10 cm long. After all the longitudinal and circular muscle fibers of the esophageal wall are cut, the muscle fibers are carefully freed between the muscle layer and the mucosa, and their width is about half of the circumference of the esophagus to prevent the formation of scars between the cut ends of the posterior muscle fibers. After freeing the muscle fibers, the mucosa is expanded from the muscle layer incision, and the mucosa is panged to the mediastinal surface as much as possible, and the diaphragmatic esophageal fissure is properly cut, which can be easily passed through one finger, and the mucosa is checked for perforation by iodine voltammetry. Surgery is simple, less traumatic, effective, less complications, surgery is the best choice for patients with ineffective conservative treatment.