What is artificial insemination? First of all, let’s talk about what artificial insemination is. Artificial insemination is the delivery of optimized sperm into the woman’s uterine cavity around the expected day of ovulation using an injection tube. Optimization means taking out the good ones, selecting millions of swimmers among hundreds of millions of husband’s tadpoles; delivery means going straight to the destination, which is equivalent to providing a special car service for the sperm to avoid quality sperm getting lost or blocked at the cervical gate. Combined with the doctor’s monitoring of ovulation, IUI delivers quality sperm to the right place at the right time, so it increases the conception rate. What kind of couples are recommended to have IUI? For men, with mild or moderate oligospermia, weak sperm, teratozoospermia; semen is not liquefied or poorly liquefied; ejaculation difficulties or autoimmune antibodies; for women, with cervicitis, thick cervical mucus, cervical fibroids and cervical had undergone conization and electroporation; with anti-sperm antibodies interfering with sperm operation and fertilization in the reproductive tract; and with difficulties in intercourse due to various reasons, all need IUI. However, most patients may be the same as Ms. Lin, semen is a little poor, after taking medication to meet the standard; fallopian tube is a little blocked, have done imaging to see the film, the situation is not serious; older, but the ovarian function is still possible, there is also normal ovulation; but can not conceive. For such couples with reduced fertility, doctors also recommend them to do artificial insemination. Why? First of all (1) there is a difference between qualified sperm and high quality sperm, and it is not easy to conceive during the ovulation period when perhaps the semen quality is low; (2) some women have excessive and sticky leukorrhea, or the cervical canal is small, which affects the sperm entering the uterine cavity; (3) the preparation period is too stressful, resulting in low male ejaculation, abnormal peristalsis of the female uterus, and less effective sperm entering the uterine cavity. So artificial insemination is also recommended for couples with reduced fertility. What is the success rate of artificial insemination? Again, the success rate of IUI is about 15% pregnancy rate by cycle. Compared to the 100% psychological expectation of infertile couples and the 50-60% pregnancy rate of IVF, IUI is indeed low; however, it is still much higher than the 0% pregnancy rate of infertile couples who have been trying to conceive for 1 year, month after month. Since human embryos have a self-elimination process, it is impossible for even a couple with normal fertility to have intercourse or IUI to achieve a single hit. What is the best time for IUI? Finally, the best time to have IUI. The best time to conceive is 3 months after the procedure. The best time to conceive is 3 months after the procedure because the patency of the fallopian tubes is improved and the endometrium is more tolerant to stimulation, which increases the fertility. If you perform IUI at this time, you will get twice the result with half the effort. Some patients, due to traditional beliefs or time constraints, always struggle with the idea of “natural” pregnancy rather than “artificial” insemination. Many patients are torn and hesitant and miss the best time to do artificial insemination and end up having to choose IVF which is more time consuming and requires more manual techniques. In ignorance and wasting time, many MM are wrong about the optimal age of conception, 25-28 years old. When pregnancy has become a difficult task, please do not miss out on the simple and helpful technique of IUI.