Emotional fatigue refers to people engaged in some monotonous and mechanical work activities for a long time, accompanied by biochemical changes in the muscle, the central local nerve cells due to continuous tension and inhibition, resulting in a significant decrease in enthusiasm and interest in work and life, until the boredom. The main manifestation of emotional fatigue is a change in behavior. Fatigue can occur in all parts of the body, from the cells of the central cerebral cortex to the basic contractile units of the skeletal muscles. The following diseases can cause emotional fatigue: 1. Chronic fatigue syndrome Chronic fatigue syndrome, also known as yuppie disease, chronic Burkitt’s virus (EBV), chronic mononuclear leukocytosis, etc. Its symptoms include fever, sore throat, swollen lymph nodes, extreme fatigue, loss of appetite, recurrent upper respiratory tract infections, small intestine discomfort, xanthogranuloma, anxiety, depression, irritability and emotional instability, sleep disruption, sensitivity to light and heat, temporary fatigue. Sensitivity to light and heat, temporary memory loss, inability to concentrate, headache, cramps, muscle and joint pain, etc. These symptoms are similar to those of the flu and other viral infections, and there is no medicine or vaccine for this virus. 2. Respiratory muscle fatigue Respiratory muscle fatigue or respiratory muscle dysfunction is very common in patients with chronic lung disease and ICU admissions, and the problem of respiratory muscle fatigue or failure has long been underappreciated. Accelerated respiratory rate, asynchronous breathing (e.g., alternating periodic abdominal and thoracic pressure breathing, staggered and non-parallel abdominal pressure breathing, abdominal bimodal row breathing movements), and thoraco-abdominal contradictory breathing. Timely detection and treatment of respiratory muscle fatigue can correct respiratory mechanics abnormalities, reduce respiratory work, improve oxygenation and shorten the duration of mechanical ventilation, therefore, in recent years, the evaluation of respiratory muscle function in critically ill patients has become one of the important elements of intensive care. 3, fatigue fractures Fatigue fractures, which are prone to occur in areas of concentrated skeletal stress, are one of the common training injuries, with a high incidence in troop training, reported as 31% abroad and 16.9% in China. Related to over-intensity training or improper posture, it occurs mostly in frequent long-distance running, cross-country training or overload training of a single course. In addition, it is also common in athletes who bear more weight on their feet, such as basketball, soccer, tennis, track and field, gymnasts and ballerinas, and also in middle-aged and elderly people who often adhere to heavy exercise. 4, metatarsal fatigue fracture athletes in running metatarsal head will produce a lot of stress, especially the first, second metatarsal head. The 2nd, 3rd and 4th metatarsal heads are prone to fracture due to their weak epiphysis. Risk factors include bowed feet, wearing shoes with poor quality of vibration reduction and osteoporosis. The weight of the foot is shifted from the first metatarsal head to the second metatarsal head, however, the second metatarsal stem is slender at the first metatarsal stem, therefore, it is prone to fatigue fractures.