Stage III nephropathy is not curable. Clinically, stage III nephropathy mainly refers to the glomerular filtration rate between 30-59 ml/min, which belongs to the compensatory stage, and some patients can have no clinical manifestations, but have already developed renal hypofunction. The purpose of treatment at this time is to delay the progression of the disease, preserve the residual renal function and ensure the quality of survival of patients. Oral medication can be applied, such as Jin Shui Bao, Bai Ling capsule, renal rejuvenation, compound alpha keto acid, ferrous succinate, medicinal carbon, oral Chinese medicine or anal plug of renal health suppository to discharge intestinal toxins, but it is difficult to make patients completely return to normal again. Be sure to inform patients of the purpose of treatment and prognosis to prevent patients from having too high expectations.