Diagnostic criteria for hepatocellular carcinoma: Liver puncture biopsy suggestive of hepatocellular carcinoma or cholangiocellular carcinoma may confirm the diagnosis; if liver puncture is not performed, the following may confirm the diagnosis: Both (1) + (2) a of the following conditions or (1) + (2) b + (3) 1) evidence of cirrhosis and HBV and/or HCV infection (HBV and/or HCV antigen positive) 2) typical imaging features of HCC: concurrent Multi-row CT scan and/or dynamic contrast-enhanced MRI showing rapid heterogeneous vascular enhancement of the hepatic occupancy in the arterial phase with rapid elution in the venous or delayed phase a. Liver occupancy ≥ 2 cm in diameter, and one of the two imaging examinations, CT and MRI, shows liver occupancy with features of hepatocellular carcinoma as described above; b. Liver occupancy of 1 to 2 cm in diameter, then both imaging examinations, CT and MRI, are required to show liver occupancy with features of hepatocellular carcinoma as described above. (3) AFP ≥ 400 μg/L for 1 month or ≥ 200 μg/L for 2 months and the ability to exclude other causes of elevation, including pregnancy, germline tumors of embryonic origin, active liver disease, and secondary hepatocellular carcinoma.