Vaginal opening pustules are commonly caused by infectious diseases such as vestibular gland cysts and folliculitis. If not well controlled, they can also cause systemic inflammatory reactions and it is recommended to actively go to the hospital for treatment. Common causes and treatments 1, vestibular gland cyst: is a relatively common gynecological inflammation, mainly due to vestibular gland duct obstruction, secretion accumulation and become. The vestibular gland cysts are relatively small, can be treated with local antibiotics, if increased or even purulent infection, need to be incised and drained; 2, folliculitis: manifested as red papules centered on the hair follicles, sometimes topped with white pustules, may have itching, tenderness or pain, location deep folliculitis pain more obvious, according to the symptoms and auxiliary examination results, the application of antibiotic treatment; 3, vulvovaginitis: vaginal opening with pus pockets It may be caused by vulvodynia, inflammation causes abscesses at the vaginal opening, it is recommended that patients go to the hospital to receive examination and treatment; 4, acne vulgaris: due to the infection of the virus leading to acne vulgaris, can appear in the urethra pus bags, it is recommended that timely treatment. If the patient has symptoms of infection such as high fever, it is recommended to go to the hospital as soon as possible.