1.Which part of the body is craniopharyngioma? Is there a high incidence? Craniopharyngioma grows in the craniopharyngeal cells in the adenohypophysis of the saddle area, which is located in the posterior lobe of the pituitary gland under the saddle septum and in the pituitary stalk over the saddle septum. The incidence of craniopharyngioma accounts for about 10% of brain tumors in children. 2. Can both children and adults get craniopharyngioma? Craniopharyngioma can occur in both children and adults. However, the incidence of craniopharyngioma in children is significantly higher than that in adults. 3.Is craniopharyngioma mainly benign or malignant? Can they become malignant? There are two pathological types of craniopharyngioma: enamel craniopharyngioma and squamous epithelial papillary craniopharyngioma. Enamel craniopharyngioma is a malignant tumor, meaning that the tumor will recur, and almost all craniopharyngiomas in children are of this type. On the other hand, squamous epithelial papillary craniopharyngioma is benign tumor, which will not become malignant and will not recur after total removal. 50% of adult craniopharyngioma are of this type, and the other 50% are enamel craniopharyngioma. 4.What are the hazards of tumor compression on nerve? Can it cause blindness? Craniopharyngioma grows in the saddle area and mainly presses on the optic nerve, which may lead to vision loss and serious blindness. 5.Will the tumor in the saddle area affect the endocrine function of the patient? What symptoms of endocrine system will appear? Craniopharyngioma will destroy the hypothalamus in the saddle area and cause endocrine function damage and endocrine hormone decline. The main manifestations of endocrine hormone decline are: short height and non-development of secondary sexual characteristics in pediatric patients, such as non-development of external genitalia and absence of menstruation; decreased libido in adults. Both children and adults may experience symptoms such as excessive drinking and urination, and fear of cold. 6.For pituitary gland dysfunction caused by craniopharyngioma in children, what problems will occur? Children’s height is significantly lower than that of children of the same age. Boys have extremely small external genitalia and do not develop by puberty; girls have no menstruation by puberty. As the development of secondary sexual characteristics is impaired, it can lead to the inability of the sick child to have children in adulthood. 7.Does the disease affect the growth and development of children? Will it cause mental abnormalities? The growth of children with craniopharyngioma is definitely affected, such as height and secondary sexual characteristics, but the intellectual development of children with craniopharyngioma is generally not affected and they can go to school normally.