Most of the joint pain in hands and feet is not an early sign of cancer, most of them are rheumatoid arthritis, gout and other diseases, but a few cancers also have joint pain in hands and feet in early stage. Patients with gout often have increased blood uric acid and may have gout stones; rheumatoid arthritis may manifest as wandering joint pain. However, patients with finger and joint pain cannot be completely ruled out for cancer, for example, lung cancer is difficult to detect in the early stage and often manifests as symptoms in other areas, such as bone and joint disease. Bone and joint lesions of lung cancer are similar to rheumatism, but they produce muscle weakness, painful swelling of large joints of the extremities, and the appearance of pestle and mortar fingers. If examined and treated according to the joint disease, the joint pain will not disappear. Therefore, for patients with joint pain in the fingers and no effect of treatment according to rheumatism, they should be alerted to lung cancer, especially smokers over 40 years old, and should have a chest X-ray at least once a year. The diagnosis of cancer cannot rely solely on joint pain, but also on other manifestations of the patient and clinical examination before the diagnosis can be confirmed.