High urinary bacilli are often a manifestation of urinary tract infections, which are examined by urine culture and cultured with increased pathogenic bacteria, at which point the patient will experience a range of urinary tract symptoms, such as frequent urination, urgent urination, and painful urination. The majority of pathogenic bacteria of urinary tract infections are Escherichia coli and Klebsiella, which are the most important causes of discomfort in urination. If the test confirms the presence of high urinary bacilli, anti-infective drugs are needed for treatment, such as quinolone antibiotics and cephalosporin antibiotics, to inhibit the presence of pathogenic bacilli in the body and achieve the purpose of restoring health. Also, during the treatment period, it is necessary to drink more water and urinate more often as appropriate. Infection may be caused by exposure to relevant contaminants or a decrease in one’s own immunity, resulting in an increase in bacterial multiplication, hence the manifestation of inflammation. If left untreated, bacterial multiplication can lead to upper urinary tract infections, such as pyelonephritis, which can cause back pain or fever.