Kidney biopsy does not usually aggravate kidney damage. For example, percutaneous puncture kidney biopsy can only obtain more than 10 glomeruli each time, which will not affect the function of the whole kidney. Generally speaking, kidney puncture biopsy is relatively safe, and serious complications rarely occur if the indications are strictly controlled and the procedure is performed according to the procedures. The common complications are: (1) Hematuria Microscopic hematuria is present in almost every case and usually disappears on its own within 1 to 2 days. The incidence of carnal hematuria is 2% to 12%, and it can be changed to microscopic hematuria in about 1 to 3 days, without special treatment, only prolonged bed rest can be done. In individual cases, hematuria is extremely serious and should be treated actively. (2) Perirenal hematoma is very common after renal puncture, mostly small hematoma, no clinical symptoms, and can be self-absorbed within 1 to 2 weeks. (3) Arteriovenous fistula typically presents with severe hematuria or (and) perirenal hematoma, intractable hypertension, progressive heart failure, and vascular murmur in the lumbar abdomen. (4) Infection The incidence of infection after renal puncture is not high, but serious infection can result in serious consequences such as renal abscess and sepsis and should be prevented.