If the acne has pus, it is not recommended to squeeze the pustules of the acne. Squeezing the acne can discharge the internal pus, which may help to reduce the symptoms, but squeezing by hand is a wrong operation, because squeezing by hand can cause the spread of local inflammation, resulting in local redness, pain, and elevated skin temperature, and even lead to enlarged lymph nodes and lymphangitis, which aggravate the inflammation. Pigmentation can be formed. If you have a pus-like pimple, you can go to the hospital to have it treated by a professional doctor, who will generally need to strengthen the anti-infection treatment. The doctor will prescribe anti-inflammatory antibiotics, such as tetracycline and erythromycin, to control the inflammation, and the pustules will slowly be absorbed and disappear after taking them. If you have a fever due to picking and squeezing the pimples, you can physically cool it down by rubbing the armpits, groin and neck with a warm towel, while seeking medical attention in time, and under the guidance of the doctor, you can take oral ibuprofen suspension for treatment.