Whenever liver cancer is mentioned, most people first think of liver pain, jaundice, abdominal distension and wasting. In fact, due to the powerful metabolic function of the liver, liver cancer has various manifestations that can be easily overlooked. These pains must be noticed! If recurrent vague pain and discomfort in the right shoulder occurs and fails to improve through appropriate treatment, it is necessary to promptly check the liver for any lesions to exclude the possibility of the existence of occult liver cancer. This is especially true for people with a history of hepatitis. However, the pain caused by internal lesions is not as accurately localized as the skin on the body, but often appears as reflex pain or involvement pain, and the pain site is not the site of the lesion. The pain in the right shoulder caused by liver cancer is referred pain, which may be caused by compression of the nearby diaphragm or muscle nerves below the lungs. The liver is located in the upper abdomen and there is no sign of liver cancer in the early stage. When the liver tumor gradually increases, it may compress the nearby diaphragm or the muscle nerves below the lungs. When the liver tumor gradually grows, it may compress the nearby diaphragm and also the muscle nerves below the lungs. Therefore, when right shoulder pain occurs repeatedly and the symptoms do not improve after proper treatment, it is necessary to promptly examine the liver to exclude the presence of lesions. Some typical symptoms of hepatocellular carcinoma will only occur when the disease progresses to the middle and late stage, and by then the opportunity of surgery is often lost, so the usual self-examination is very important. When fatigue and weakness cannot be relieved, it is likely to be an omen of liver disease; dullness in the heart fossa, or dull pain in the upper right side of the abdomen, pressure and discomfort, weight loss, unexplained fever and jaundice, etc. The best way to prevent liver cancer is to maintain health, pay attention to personal habits, eat more health food, regular maintenance and conditioning, and maintain a healthy state of mind.