Uric acid is the end product of purine metabolism, the saturation and concentration of uric acid in the body at 37°C is about 420μmol/L (7mg/dl), exceeding this concentration is hyperuricemia, and long-term hyperuricemia may lead to gout. Clinically, it is divided into primary hyperuricemia and secondary hyperuricemia, so its treatment includes the following aspects: primary hyperuricemia and gout treatment for lowering uric acid includes: 1. General treatment: control total dietary calories; limit alcohol consumption and large intake of high purine food; drink a lot of water to increase uric acid excretion; use drugs that inhibit uric acid excretion such as thiazide diuretics with caution; avoid triggering factors and actively treat Related diseases. 2.Treatment of hyperuricemia: The aim is to maintain the normal level of uric acid. Mainly include: uric acid excreting drugs such as benzbromarone, drugs that inhibit uric acid production such as allopurinol, alkaline drugs such as sodium bicarbonate, new uric acid lowering drugs such as selective uric acid reabsorption inhibitors. 3. Treatment of acute gouty arthritis phase: long-term hyperuricemia may lead to gouty arthritis. Colchicine, non-steroidal anti-inflammatory drugs and glucocorticoids are the first-line drugs for the treatment of acute gouty arthritis and should be used early. Management of interictal and chronic phases of gout attacks: For patients with frequent attacks of acute gouty arthritis, chronic gouty arthritis or gout stones, uric acid-lowering therapy should be performed. Treatment principles for secondary hyperuricemia: actively treat the primary disease; avoid or minimize the use of drugs and methods that may trigger and/or aggravate hyperuricemia; control the acute gouty arthritis attack as soon as possible. In addition, hyperuricemia and gout are often associated with metabolic syndrome, so comprehensive treatment such as blood pressure lowering, lipid lowering, weight reduction and improvement of insulin resistance should be actively carried out. Therefore, to lower uric acid, we should choose the appropriate method according to the cause and condition of the patient, and we should combine medication and general treatment in order to achieve better results.