HPV, or human papillomavirus, is a spherical DNA virus, and HPV type 16 and HPV type 18 are more difficult to treat. These two types are more difficult to turn negative after infection, but it does not mean that there is no possibility of cure, while other high-risk HPV types are also at higher risk. With the development of molecular biology technology, there are hundreds of HPV types, and HPV is differentiated into high-risk and low-risk types for the risk of malignant tumor development. There are 13 types of high-risk HPV, which have a high probability of causing cervical lesions, including HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68, and the occurrence of cervical cancer is closely related to persistent high-risk HPV infection. There are 12 types of low-risk HPV, including HPV types 6, 11, 40, 42, 43, 44, 53, 54, 61, 72, 73, and 81. When HPV infection occurs, colposcopy and liquid-based thin-layer cytology should be performed promptly to determine the typing of HPV, which is helpful for clinical diagnosis and can also reduce unnecessary fear of patients. At the same time, it is important to get enough sleep, avoid staying up late, keep a happy mood, and do moderate physical exercise to strengthen the body’s immunity. When having sex, pay attention to protection to avoid cross-infection.