Clinically, for patients with simple pneumothorax, the junction of the midclavicular line and the 2nd intercostal space is often chosen for puncture and placement of a drain. For patients with moderate to large amount of fluid pneumothorax, the location of the puncture can be appropriately shifted downward intercostally, usually from the anterior axillary line to the 7th-8th intercostal space in the mid-axillary line. In clinical practice, when we encounter wrapped pneumothorax or limited pneumothorax, the location of the largest amount of pneumothorax is located by chest X-ray or CT for puncture and placement of drainage tube. Therefore, the location of closed drainage puncture of pneumothorax should be decided according to the specific situation of the patient and the characteristics of imaging changes of chest X-ray or CT. When the puncture location is not good or when it is difficult to correct the pneumothorax, surgery can be performed if necessary.