Liver cancer refers to malignant tumors occurring in the liver, including primary liver cancer and secondary liver cancer, and people mostly refer to primary liver cancer when they talk about liver cancer in daily life. All kinds of cancer, when developed to a certain extent, may metastasize to the liver. At present, liver cancer ranks fourth in the incidence rate of malignant tumors in China, but second in the mortality rate of malignant tumors. In terms of the geographical distribution of cancer in China, liver cancer is mainly concentrated in the southeastern coast as well as the northeastern Jilin region. Since the liver is the largest substantial organ of human body and is responsible for various important metabolic functions of human body, once malignant tumors appear in the liver, it will seriously threaten the life of patients and has a high mortality rate. In addition, malignant tumors of liver are insidious, aggressive and fast growing, and very difficult to treat. Therefore, early detection, early diagnosis and early treatment are extremely important. The following are the early symptoms of liver cancer: liver cancer often does not have specific early symptoms, but it is often found as a solid occupancy in the liver during normal physical examination. 1.History of hepatitis and cirrhosis, stable condition for many years, no chills and fever, but sudden onset of dull pain or severe pain in the liver and biliary area. 2.Masses can be found in the right upper abdomen and epigastrium with hard texture and uneven surface, and the tendency of enlargement is obvious under continuous observation, while the patient has no obvious discomfort. 3.Dry mouth, irritability, insomnia, gum and nasal bleeding, accompanied by epigastric distention and fullness and discomfort in the liver area. 4.Sore joints all over the body, especially in the lower back, accompanied by anorexia, irritability, discomfort in the liver area, and those with poor results after anti-rheumatic treatment. 5.Recurrent diarrhea accompanied by indigestion and abdominal distension, and the effect of treatment according to gastroenteritis is not obvious or cannot be cured, and there is stuffy pain in the liver area and gradual wasting. Prevention is the most important for the control of any disease. Then what should be noted in the prevention of liver cancer? 1. Hepatitis B vaccination. Since the occurrence of liver cancer is very closely related to hepatitis B, especially in developing countries, the rate of hepatitis B surface antigen positivity in the serum of liver cancer patients is greater than 50%. The World Health Organization conference on liver cancer prevention pointed out that the correlation between hepatitis B virus and liver cancer is as high as 80%. Therefore, hepatitis B vaccine is regarded as the first “anti-cancer vaccine”. Therefore, hepatitis B vaccination is one of the most important measures to prevent liver cancer. 2.Control hepatitis C. It is reported that 28.5% of hepatitis B surface antigen negative liver cancer patients are positive for hepatitis C antibody, which shows that hepatitis C virus is an important carcinogenic factor of liver cancer. 80%-90% of hepatitis C is transmitted by blood and blood products, so minimizing blood transfusion or application of blood products is another effective measure to reduce hepatitis C and control the occurrence of liver cancer. 3. Do not eat moldy food. The carcinogenic effect of aflatoxin is 75 times greater than that of nitrosamines, and it can induce liver cancer in all animals, although the problem of inducing liver cancer in humans is still inconclusive, scholars believe that it is one of the initiating factors of liver cancer. Therefore, do not eat food suspected of having mold or mold has occurred. 4. Do not abuse alcohol. Data show that alcoholism is related to the occurrence of liver cancer, and patients with alcoholic cirrhosis have a high chance of developing liver cancer, so don’t abuse alcohol. Generally speaking, healthy people should drink less, and those with liver disease should avoid alcohol. 5.Patients with hepatitis or cirrhosis should pay attention to regular review of ultrasound, liver function and hepatobiliary tumor indicators such as AFP, CEA and CA199 (once every 3-6 months), and promptly seek specialist consultation if there is any abnormality. 6.Other aspects. Drinking water contamination, drug poisoning, smoking, nitrosamines, lack of trace elements and genetic factors all have synergistic effects on cancer. Therefore, comprehensive measures such as environmental protection, hygiene, nutrition, drug abuse and poor hygiene should be taken to effectively prevent the occurrence of liver cancer.