Male infertility is a complex and more difficult problem to solve, but should not be pessimistic. In diagnosis, the first step is to find the cause of infertility and then treat it. The treatment of male infertility includes etiologic treatment, endocrine treatment, and non-specific treatment. There are some male infertility patients with organic lesions that can’t be solved by drugs and can only be treated by surgery. There are mainly the following categories: 1, genital malformation or developmental abnormalities Commonly, there are cryptorchidism, urethral stenosis, urethral fistula, hypospadias, supraspadias, and severe penile sclerosis. 2.Obstructive azoospermia Including obstructive azoospermia caused by congenital defects of the vas deferens and seminal vesicles; segmental hypoplasia of the vas deferens; medical injury or ligation of the vas deferens; congenital stenosis of the ejaculatory duct orifice and so on. 3, varicocele In male infertility, the incidence of varicocele is as high as 20% ~ 3 5%, the use of high spermatic vein ligation treatment, can make some patients restore fertility. 4.Organic sexual dysfunction Including impotence caused by severe penile trauma, pelvic fracture, vascular factors (such as venous fistula) or neurological disorders, and some patients with retrograde ejaculation caused by organic lesions.