The reason why gout attacks at night is also a concern for many people, there are two reasons: 1 is the easy deposition of uric acid at night 2 is the low level of glucocorticoids at night, anti-inflammatory pain relief shot uric acid power is poor. A, night uric acid easily deposited It is currently believed that gout attacks are related to urate crystals, precipitation of urate crystals, deposited in the joints on the occurrence of acute gouty arthritis. The solubility of urate is affected by the concentration of uric acid in the body, blood circulation, and local temperature. Because of the low temperature and slow blood flow at night, coupled with the low water intake at night, the blood is more viscous, making it easy for uric acid to accumulate locally and reach a certain concentration, precipitating crystals and triggering arthritis. Second, low hormone levels at night Glucocorticoids help to drain uric acid, but also anti-inflammatory and pain relief, gout patients with hormones in the acute phase can make the disease quickly relieved. Glucocorticoids are generally secreted at about 8:00 a.m. and reach their peak at noon, while midnight is the low point of hormone secretion. The role of hormones in the body reaches a low point before midnight, and the level of human metabolism is very low before midnight, which makes it easy for gout to strike. Because gout is obvious at night, so the author generally recommends that painkillers be taken after dinner. Chinese medicine explanation: Chinese medicine meridian theory that “Hai Jiao Zi Bile Ugly Liver”, 1:00 to 3:00 at night is the detoxification time of the Foot Turk Yin Liver meridian. Because uric acid is formed by the weak detoxification function of the liver, Chinese medicine often identifies it as damp heat in the liver meridian, and the first metatarsophalangeal joint is a joint that follows the liver meridian, so this joint is a good site for gout. The first metatarsophalangeal joint is the joint of the liver meridian, so this joint is the site of gout. According to the “Guezhi Yu Lun? The Gout Theory points out that the gout is caused by the heat of the blood, which has been boiling since, after that or wading in cold water, or standing on wet ground, or fan to get cool, or lying when the wind, cold and cold outside the fight, hot blood to get cold, foul condensation, so pain; at night, the pain is even, line in the yin also. The treatment is to use a pungent and hot agent to disperse the cold and dampness, develop the coup, the blood can travel and harmonize with the gas, the disease will be safe. The author understands that Danxi refers to “Wei Qi”. The “Ling Shu, Wei Qi Xing” says: “The movement of Wei Qi is 50 weeks around the body in a day and a night, 25 weeks in Yang and 25 weeks in Yin at night. Therefore, the author believes that gout is a disease of yin evil, and its location is often in the lower part of the body, in the tendons and bones (yin position), not in the upper part, not in the skin and hair. When the Wei Qi travels through the Yang meridian, it cannot compete with the evil and therefore does not hurt. When it travels through the Yin meridian, it is painful because of the fight between the positive and the evil.