1. General treatment of sepsis Ensure that the patient has enough water and vitamins. Rest in bed, strengthen nutrition, and ensure patients have enough water and vitamins; for patients with little food and vomiting and diarrhea, intravenous rehydration is required to maintain water and electrolyte and acid-base balance. Strengthen nursing care, pay attention to oral hygiene and skin cleaning to prevent secondary infections and decubitus ulcer formation. 2. Symptomatic treatment of sepsis High fever and chills, use compound aminopyrine 2ml intramuscular injection. For hyperthermia, consider subhypothermia therapy. While giving hibernation drugs, place ice packs on the head and neck, axillae and groin to maintain the body temperature at about 38℃. Sedation is given to those who are irritable to reduce symptoms and patient distress. For convulsions, use luminal 0.1g intramuscularly. In severe toxemia such as toxic shock, toxic myocarditis, a brief 3-5 adrenocorticosteroid treatment with hydrocortisone 200-300 mg daily or dexamethasone 10-15 mg daily can be given along with full use and effective antibacterial drugs. in infectious shock treatment of DIC, multi-organ failure, the appropriate measures should be taken. Patients may be given fresh blood or gamma globulin to improve their physical condition. 3. antimicrobial treatment sepsis Empirical treatment with antimicrobial drugs should be given according to the situation. Once sepsis is diagnosed, empirical antimicrobial therapy should be administered as appropriate before pathogenic results are available. Later, the dosing regimen will be adjusted according to the pathogenic bacteria and the results of the drug sensitivity test. Antimicrobial treatment of sepsis can be a combination of two effective antimicrobial drugs, which should be administered intravenously at high doses in order to ensure appropriate plasma and tissue drug concentrations. A bactericidal agent should be selected. A longer course of treatment is desirable, usually more than 3 weeks, or the drug should be continued for 7-10 d after the temperature has dropped to normal and the clinical symptoms have disappeared.