Hepatitis B vaccination is not a lifelong immunization. Antibodies produced after vaccination against hepatitis B will gradually decrease with the passage of time, and the immune function produced will also decrease year by year, and eventually disappear completely, and it is not lifelong. After hepatitis B vaccination, the human body will show positive surface antibody, which is the activation of the immune system of the human body, and can protect the human body from being infected by the hepatitis B virus in the event of infection by the virus. Hepatitis B vaccination is not lifelong, so it is best to have yearly checkups after receiving Hepatitis B vaccination. If a decrease in hepatitis B antibodies is detected, it is sufficient to follow the requirements of the catch-up vaccination, which can reactivate the body’s immune response. Therefore, it is recommended to have regular medical checkups and follow the doctor’s instructions for hepatitis B vaccination.