Intraductal papillomas are usually seen in women aged 40-50 years, often occurring singly or in multiple ducts near the nipple, and are generally small, vascular and bleeding. Etiology Intraductal papilloma is benign, but there is a possibility of malignant transformation, with a malignancy rate of 6%-8%. The main clinical manifestations are usually no conscious symptoms, but often attract attention because the nipple overflow pollutes the underwear, which can be bloody, dark brown or yellow liquid. The tumor is small and often not palpable, occasionally there is a larger mass. Large ductal papilloma, small nodules of several millimeters in diameter, mostly round, soft and pushable, can be found in the areola area, and bloody fluid can often come out from the nipple when the mass is lightly pressed. Auxiliary examination Mammography can clarify the size and location of the tumor in the ducts; endoscopic examination of the ducts is also possible, in which a light duct with an inner diameter of less than 1mm is inserted from the overflowing duct of the nipple to observe the situation in the ducts through endoscopic imaging technology. V. Treatment principles Treatment is mainly surgical, and the lesioned milk duct system should be removed for single intraductal papilloma. Prior to surgery, correct positioning is required, and the overflowing milk duct opening is determined by finger pressure, a blunt-tipped fine needle is inserted, or US blue can be injected, and a radial incision is made along the needle or US blue coloring site to remove the test milk duct and surrounding breast tissue. Pathological examination should be performed routinely, and radical mastectomy should be performed if there is malignant change. Nursing measures 1. Inform the patient of the etiology of nipple overflow and the necessity of surgical treatment, and contact the patient’s ideological concerns. 2. Keep the incision dressing clean and dry after surgery, and return to the hospital for dressing change on time. 3. Return to the hospital for review regularly. 7. Preventive care 1. Perform regular breast self-examination or go to the hospital for breast examination. 2. As far as possible, women of appropriate age should not give up childbirth and breastfeeding because of career or other reasons. 3. Do not be overly emotional or overly depressed.