The pathogenesis of leukemia is complex, and basically there is no relevant literature to clarify the pathogenesis of leukemia, only to point out that there may be causative factors that lead to leukemia. However, there is a clinical problem that even if there are causative factors for leukemia, such as formaldehyde in the renovation process can induce leukemia, in most cases, it does not lead to leukemia, and the cause is related to the body’s own genes. The human body has a proto-oncogene, which means that this gene may cause cancer, but there are some other genes in the human body, such as oncogene, and a small amount of oncogene may suppress the proto-oncogene. If the proto-oncogene and oncogene are in balance, leukemia will not occur. If this balance is disturbed, for example, the oncogene is suppressed and the proto-oncogene is amplified, the body may be prone to leukemia.