Patient: Description of the condition (onset time, main symptoms, hospital visited, etc.): The disease flared up in 2007, and is now being seen at your hospital It is basically under control There is a fingernail pain, is it a sign of rebound. Should I go for a review? Rheumatology and Immunology Cai Xiaoyan, Guangzhou First People’s Hospital: Common manifestations of SLE flare-ups include: fever, joint swelling and pain, rash, swelling, headache, etc. Fingernail pain alone is not a manifestation of lupus relapse. Regardless of the presence or absence of uncomfortable symptoms, SLE needs to be reviewed regularly. If the disease is unstable, it should be checked at any time; if the disease is stable, it should be checked once every three months; if the disease is very stable, it should be checked once every six months. Regular review and timely adjustment of treatment are the keys to control the long-term stability of the disease.