Demyelinating changes in the white matter of the brain in the elderly is a subcortical atherosclerotic encephalopathy, formed because the brain is in chronic ischemia and hypoxia, the most common causes are related to cerebral atherosclerosis and insufficient blood supply to the brain. Patients may exhibit memory loss and cognitive decline, similar to dementia, and may have strong crying and laughing, as well as behavioral abnormalities, such as indifferent expressions, or some emotional problems. Therefore, when an elderly person has a CT or MRI of the head and a relatively heavy demyelination of the white matter of the brain is detected, secondary prevention of cerebrovascular disease must be initiated. It is recommended that patients be given drugs to activate blood circulation and remove blood stasis, such as oral ginkgo biloba dripping pills, blood serum tablets, vermifuge and snake capsules, and strict control of blood pressure, blood lipids and blood sugar, and oral aspirin to antiplatelet aggregation.