Liver tumors are divided into two types: malignant and benign. Not all liver tumors are hepatocellular carcinoma. The common malignant tumors are hepatocellular carcinoma, including primary liver cancer and metastatic liver cancer. The most common benign liver tumor is hepatic cavernous hemangioma. Clinically, liver cancer is often confused with hepatic cavernous hemangioma, especially it is difficult to distinguish small hemangioma from small hepatocellular carcinoma. Hepatic cavernous hemangioma is commonly seen in middle-aged women, and is mostly solitary or can be multiple. It is mainly diagnosed by X-ray examination, B-ultrasound examination, CT examination, MRI examination and clinical manifestations of the disease. The clinical manifestation of tumor is slow growth, long course, smooth surface of larger tumor, medium texture with elasticity and compressibility, and almost no obvious symptoms, which are mostly found during physical examination. Patients also have no history of liver disease, negative for methemoglobin, and imaging examination can make a clear diagnosis. In contrast, although CT of liver cancer is also obviously enhanced in early stage, it lasts for a short time, and most of them appear obvious fading in the venous stage and close to the flat scan density. Small hepatocellular carcinoma shown by ultrasound mostly shows weak echogenicity and thin wall, while weakly echogenic hemangioma has thick wall. Marginal splitting sign and vascular entry sign are not visible in hepatocellular carcinoma masses. And imaging examinations such as ultrasound and detection of alpha-fetoprotein (AFP) can help in the early diagnosis of liver cancer, and even detect micro or small liver cancer without symptoms and signs. Most patients with hepatocellular carcinoma have significantly elevated levels of AFP in blood (400 μg/L). Although hepatocellular carcinoma is difficult to distinguish from hepatic cavernous hemangioma, it can be diagnosed by imaging, detection of tumor serum markers and clinical manifestations.