Although the incidence of neocoronavirus in children is low compared to other age groups, children are equally susceptible to novel coronavirus. At the beginning of the epidemic, because of the incomplete understanding of the novel coronavirus and the relatively small number of cases in children, some people believed that the novel coronavirus was not easily infected in children based on the epidemiologic data available at that time, but as the number of infections expanded, clinical studies and epidemiologic trends showed that the novel coronavirus was universally infectious in all populations. Because of the mild symptoms and non-characteristic clinical presentation in children with neo-coronavirus, it is more important to be vigilant and to observe and judge carefully. Fever and cough are common manifestations of neo-coronavirus infection in children and may be accompanied by some cold symptoms such as runny nose, sneezing, sore throat, and possibly fatigue, myalgia, vomiting, and abdominal pain, but some children have no fever symptoms after infection and only show cough or diarrhea. Some children and newborns show gastrointestinal symptoms such as vomiting and diarrhea, or only asthma and shortness of breath. There are few cases of neonatal infection in children, and there are no large-scale research findings. If parents notice any of these symptoms and suspect neonatal infection, they should take their children to the hospital for examination and active treatment as soon as possible, especially for children with underlying diseases or comorbidities. Therefore, children also need to pay attention to daily protection, wear masks when going out, try to stay away from public places where people gather and the environment is confined, and avoid close contact with poultry or wild animals as much as possible. Disinfect and wash hands in time after returning home, disinfect and ventilate the room regularly, and open windows in winter to prevent colds.