Numbness in the hands and feet is referred to neurology. Most patients present with numbness in the hands and feet, which is caused by neurological disorders. It is usually common in cerebrovascular diseases including cerebral infarction in the basal ganglia area, radiocoronal area, and may also be caused by small brain hemorrhage. The disease usually occurs in middle-aged and elderly people with acute onset. Common causes include hypertension, diabetes mellitus, hyperlipidemia, hyperhomocysteinemia and cerebral aneurysm and atherosclerosis, among others. If a patient develops the disease, a cranial CT or MRI should be performed promptly to clarify the diagnosis. Most patients with this disease have persistent symptoms and should be promptly hospitalized for comprehensive treatment after the onset of the disease. If the patient’s symptoms are episodic, they may also be caused by insufficient blood supply to the anterior circulation. Most patients have symptoms that last anywhere from 10-15 minutes and rarely last longer than half an hour. In general, the cranial CT examination is normal, but it may also progress to cerebral infarction when it occurs frequently, and should be given promptly as treatment. Oral aspirin antiplatelet aggregation treatment can be given, and statins are also applied to stabilize the plaque. If the patient has numbness in both hands and feet, it may be caused by peripheral blood circulation disorder, which can be seen clinically in patients with chronic cerebral blood supply deficiency, and may also be caused by poor long-term blood sugar control in diabetes.