Numbness of hands and feet in middle-aged and elderly people may be a sign of cerebrovascular disease or peripheral neuritis, cervical and lumbar spine disease or caused by poor peripheral blood circulation. The specific analysis should be combined with the form of patient onset: 1, the most critical, if the middle-aged and elderly people appear unilateral numbness of the hands and feet, consider the signs of cerebral infarction brain hemorrhage, to immediately consult the hospital for examination and treatment. 2, if the patient is inappropriate posture of the hands and feet numbness symptoms, consider the cervical and lumbar spine disease. 3, if the patient is diabetic or long-term smoking, drinking alcohol, exposure to chemical toxins, resulting in the hands and feet of the limbs of the disease. The patient’s hands and feet are numb at the end of the extremities due to exposure to chemical toxins, consider the problem of peripheral neuritis, the patient should improve the electromyography examination. 4, if the patient’s hands and feet are numb in case of cold, consider the patient’s poor peripheral blood circulation.