9, laboratory tests The disease lacks sensitive and specific early laboratory diagnostic methods. Some patients have abnormal lipid metabolism. The main manifestations are blood total cholesterol, triglyceride, LDL cholesterol, ApoB ↑; ApoA, HDL cholesterol ↓; Lp(a) ↑. 10.Diagnosis: The early diagnosis of this disease is not easy and very difficult. However, we can consider several aspects provided in the following diagnostic bases. 10.1 Diagnostic basis: people over 40 years old; abnormal lipid metabolism; “atherosclerosis” and “cognitive deficiency” etiology. 10.2 Diagnostic model: diagnosis of disease name, diagnosis of disease cause, diagnosis of disease mechanism and pathology, diagnosis of staging and evidence.