Bilateral pleural effusion treatment first need to clarify the cause of the disease, common causes are tuberculosis, pneumonia and pyothorax, malignant tumors, etc., treatment methods include drug treatment, surgical treatment, etc., the use of drugs follow the doctor’s instructions. 1. Tuberculosis: pleural effusion caused by tuberculous pleurisy requires regular anti-tuberculosis treatment, such as isoniazid, rifampicin and so on. 2. Pneumonia and pyothorax: anti-infection to control pleural effusion, such as the use of cefepime and other antibiotics to promote absorption. If the amount of effusion is large, it is necessary to consider closed drainage of the chest cavity. Purulent pleural effusion can be treated with repeated pleural cavity irrigation. 3. Malignant tumor: treat the primary tumor, use chemotherapeutic drugs such as cisplatin, etc., and local radiotherapy if there is lymph node metastasis. If the symptoms of dyspnea are serious, a drain can be placed in the intercostal space. If bilateral pleural effusion occurs, it is recommended that the patient should seek medical treatment in time to avoid delaying the condition.