The vast majority of patients with bone metastases ultimately die from the primary, with an average survival time of 6-48 months reported in the literature. The aim of treatment for bone metastases is to relieve symptoms and control bone pain, prevent or reduce complications, improve survival quality and prolong life. Therefore, multidisciplinary and multimodal comprehensive treatment is required, including medical oncology, tumor radiotherapy, orthopedics, radiology and nuclear medicine. Before treatment, every effort should be made to understand the patient’s general condition, age, whether the lesion is single or multiple, and whether the primary lesion is clear. Different treatment options should be chosen according to the situation. The treatment should be carried out by specialists, and cytotoxic drugs can be applied to carry out systemic chemotherapy. Hormone therapy can be useful for patients with breast cancer or prostate cancer. Radiation therapy can be effective in patients with bone metastasis of thyroid cancer. The latest literature reports that bisphosphonates have been widely used in the treatment of tumor metastatic bone disease and have been proved to be safe and effective, and the development and application of the new generation of bisphosphonates provide better choices for patients with bone metastases. And for impending or already occurred pathologic fracture, surgical treatment should be taken. For the prevention of pathologic fractures and the treatment of fixation surgery, the indications for surgery are currently controversial, mirel elaborated a scoring system for evaluating the risk of fracture, including 4 reference indicators: 1, lesion site, 2, type of bone destruction, 3, number of bone destruction, 4, and the pain index Each indicator is divided into 3 grades, with an overall score of more than 10 points easy to fracture, and less than 7 points not easy to fracture. That is to say, weight-bearing bone cortical osteolytic destruction of more than 50%, pain during weight-bearing, or extensive osteolytic destruction of the proximal femur are prone to fracture. The indications for surgery for bone metastases can be summarized as follows: 1. People with intractable pain; 2. People with spinal metastases that trigger neurological symptoms for no more than 3 weeks, persistently aggravating neurological damage, and with an estimated survival longer than 3 months; 3. People with pathologic fracture of the long tubular bone, or those on the verge of a pathologic fracture, with an estimated survival of more than 6 weeks; 4. People with pelvic lesions that are ineffective in treatment by radiotherapy, chemotherapy, and other treatments, and are estimated to survive for more than 4 weeks; and 5, ECT only found a single metastatic foci, and the tumor primary has been eradicated or widely resected; 6, the main organs are still functional and can withstand surgery. Two basic principles must be kept in mind: (1) prophylactic immobilization of impending pathologic fractures is easier; and (2) prophylactic immobilization has fewer complications than post-fracture immobilization. Appropriate surgical design is made more challenging by the fact that the patient’s survival time cannot be predicted. The chosen method of fixation must be strong enough to permit full weight-bearing ambulation in the immediate postoperative period. Since the patient may only survive for a few months, he or she should not be allowed to recover in bed for a long period of time. At the same time, the reconstructed material should be durable enough to be applied to the patient for many years, as sometimes the patient will have a good outcome and survive for a long time. In general, the tumor should be removed prior to internal fixation and the cavity created filled with bone cement. Tumor removal with prosthetic replacement may also be considered. As the bone often requires radiotherapy, the prosthesis should be fixed with bone cement. 3 weeks after surgery, if the incision heals well, arrangements can be made to do field radiotherapy. Immunotherapy and Chinese herbal medicine treatment can be applied as appropriate. Wang Moumou, a 77-year-old male, was admitted to the Department of Urology of our hospital because of prostatic hypertrophy, and the whole body PET-CT examination did not find a clear primary tumor. X-ray examination of left foot pain showed osteolytic lesion of left navicular bone, and he was transferred to orthopedic department for treatment.CT examination showed lesion of left navicular bone with bone destruction. In order to relieve pain and restore function, the orthopaedic department performed internal scraping of the tumor lesion and Kirschner’s pin bone cement internal fixation.