Bone metastases are common and occur in many advanced cancers. Bone metastatic lesions are histologically and biologically consistent with the primary lesion. Bone metastatic cancer’s most commonly occur in the spine, pelvis, and proximal femur and humerus, and the earliest symptom is pain, which can occur days or weeks before evidence of x-ray destruction. The pain can be deep, dull, intermittent and not related to activity. The pain usually wakes up at night and nocturnal pain is a feature. In later stages, the pain can be severe and persistent. The main goals of bone metastasis cancer treatment are to improve quality of life and prolong life. Many cancers still have long survival period after bone metastasis, in order to improve patients’ quality of life and prolong the survival time should be actively treated, including symptomatic pain relief, inhibition of bone destruction, radiotherapy, chemotherapy and surgical removal of bone metastasis, especially when there is the danger of pathological fracture and paraplegia should be actively operated. The treatment of bone metastatic cancer is a comprehensive treatment, and a reasonable plan must be formulated according to the specific condition of the patient.