Menopause generally refers to the longer period of transition from the reproductive stage to the menopausal stage. The average is about 50 years old. Women who are in this period experience some special physical and psychological problems. Physiologically, this is characterized by atrophy of the genitourinary organs, unstable vasomotor activity and irregular menstrual bleeding. Sometimes there are hot flashes and night sweats, and in some cases there is vertigo, dizziness, palpitations and anxiety. And psychologically, there are often some anxiety, depression and even neurotic manifestations. This leads to easy fatigue, anger, irritability, depression, temper tantrums, etc. in this category of patients. The above changes in women during this period can be clearly appreciated for the following reasons. In many families, the children have left the family or have started their own families during this period. The “empty nest” phenomenon is one of the factors that can cause depression or anxiety among mothers who have been caring for and maintaining the family. In addition, women’s own physiological changes such as the depletion of gonadal endocrine secretions can also hit them both mentally and physically. For many menopausal women, the end of the current phase of life and the beginning of a new one is one of the reasons for psychological stress. The decline in physical ability and the advancing age will give them a sense of urgency and anxiety, and they will make adjustments to their work and life. In the process of adjustment, once there is something unsatisfactory will stimulate their bad emotions, strong dissatisfaction and even resentment towards people and things around them. At this time, most of the marital life has returned to dull, poor communication between the couple will make patients feel that no one can understand themselves no one can understand themselves, the accumulation of bad emotions can not be effectively ventilated, after the outbreak will seem unmanageable. Every time the patient is finished with her whining and temper tantrum, she feels guilty and blames herself, but afterwards she is still unable to control herself and is caught in a vicious circle. In short, menopausal women are in a special physiological and psychological stage, and the so-called “menopausal syndrome” should be viewed and analyzed in this specific context. The first step is to be able to face the physiological changes and to develop a medication plan according to the different reactions of each patient. Second, psychologically, the family should be able to understand the patient’s state of mind, create a positive and gentle communication environment, and encourage the patient to use appropriate ways to vent his or her emotions. Children can communicate with their mothers more often so that they do not think that they are “useless and useless”. When they are anxious or even angry, they should deal with them calmly and not confront them head-on, as this will only reinforce her angry thoughts and behaviors. Patients should also be able to recognize and appreciate these changes in themselves during this period, cultivate more other interests and hobbies, and learn to relax themselves. It may be good to talk to a psychologist if necessary.