Most patients with purpura nephritis can survive for a long time, and a few patients may die within a few years due to inactive treatment. Purpura nephritis is a secondary nephritis, mainly caused by allergic purpura, and its clinical manifestations are mainly skin purpura, joint swelling and pain, abdominal pain, proteinuria, etc. Generally speaking, the cure rate of purpura nephritis is moderate, depending on the extent of the patient’s lesions and whether early intervention. For patients with milder lesions, the prognosis is good and early active treatment can lead to a cure that does not affect the patient’s life. However, if the patient has a rapid deterioration of renal function, it may eventually develop into renal failure. For patients with renal failure, early standardized and systematic dialysis treatment can help patients survive for decades. Patients are advised to exercise properly to enhance body resistance, avoid cold and strain, and actively cooperate with the doctor’s treatment recommendations. TCM blood activation and detoxification therapy is very advantageous in the treatment of purpura nephritis.