Those with infective endocarditis should undergo surgery if there are redundancies, valve perforations, tears, or pus cavities on the valve to prevent redundancy from dislodging causing brain, kidney, or spleen embolism and treating insufficiency caused by the valve lesion. Cardiac surgery is advisable in infective endocarditis using high doses of strong antibiotics to control the infection for 4 to 6 weeks before surgery to avoid the risk of surgical infection, as well as tissue edema and fragility that can be fatal. However, for infective endocarditis that cannot be controlled by drugs, when severe cardiac dysfunction occurs and emergency surgery is required, emergency surgery to expel the infected foci, replace the prosthetic valve and remove the abscess cavity to improve cardiac function can be performed with strong antibiotics, followed by further intensive anti-infective therapy. Patients and families should be informed that the risk of surgery when the infection is uncontrolled is very high, and that failure to operate may be immediately life-threatening.