Patients with obvious edema caused by staying up late can generally be eliminated by the following methods: a. Patients can take appropriate refreshment sleep to make the body fully rest and relieve fatigue, thus improving the exertional state of the body, which can help reduce the symptoms of edema. Patients can apply blood circulation ointment and massage physiotherapy to improve the local blood circulation and promote the faster decreasing of edema symptoms. Patients can take oral medications to reduce edema, such as Mizarin and Furosemide tablets, to reduce the aggravation of edema symptoms in the body, promote water metabolism and relieve edema symptoms. 4. Improve the habit of staying up late and regular rest and rest time, otherwise, after the treatment of edema is completed, continuing to stay up late will cause recurrence of edema symptoms.