The most common type of warts is the human papillomavirus (HPV), which is a sexually transmitted disease that occurs in the anus and external genitalia. The main reason for this is that HPV is the only host of HPV, and the virus that causes warts is HPV-6, 11, 16, 18, etc. HPV mainly infects epithelial tissues, and studies have shown that HPV plays a role in the development of anal genital cancer, such as HPV-16, 18, 45, 56, which are the most common high-risk types for cervical cancer. Transmission route] is mainly transmitted directly through sexual contact. Clinical manifestations】The disease is usually found in sexually active young and middle-aged people. The incubation period is generally 2 weeks-8 months, with an average of 3 months. The external genitalia and the mucous membrane of the skin around the anus are the preferred sites. In men, the lesions are found in the coronal sulcus, foreskin, glans, ligament, urethra, penis body, perineum, in homosexuals, in the anus and rectum, and in women, in the labia majora and minora, vaginal opening, clitoris, vagina, cervix, perineum and perianal area. The lesions start as single or multiple scattered reddish papules with soft texture and sharp tips, which gradually increase in size and can be papillate, cauliflower, or coronary. The warts are often white, pink, or gray, and the surface is prone to erosion, oozing, maceration, and rupture, and can be combined with bleeding and infection. The majority of patients have no obvious conscious symptoms, a few may have foreign body sensation, burning pain, itching or discomfort during sexual intercourse. It may increase in size and size during pregnancy. Clinically, there are latent and subclinical HPV infections. The former has a normal appearance of local skin and mucous membrane and a negative white acetate test, but the presence of HPV can be detected by molecular biology methods, HPV latent infection is one of the main reasons for the recurrence of condyloma acuminata; the latter is manifested by lesions that are not recognizable to the naked eye, positive white acetate test or with typical histopathological manifestations, the presence and reactivation of subclinical infection is related to the recurrence of the disease. The latter manifests itself in the form of lesions that are not recognizable to the naked eye or typical histopathological manifestations.