Condyloma acuminatum is a clinically common sexually transmitted disease caused by human papillomavirus (HPV) infection. It is a very common disease caused by the human papillomavirus (HPV). It is highly contagious, easily recurring, and has a long treatment period. At present, more than 100 HPV subtypes have been found, which are divided into two categories: low-risk and high-risk according to their pathogenic power or cancer risk. Low-risk HPV mainly causes anal skin and male external genitalia, female labia majora and minora, urethral orifice, lower vaginal ectoplasmic warts, and low-grade cervical intraepithelial neoplasia, and its virus subtypes are mainly HPV6, 11, 30, 39, 42, 43; high-risk HPV can cause external genital warts, but more importantly, it causes external genital cancer, cervical cancer and high-grade uterine intraepithelial neoplasia. Some scholars also classify HPV subtypes into low-risk, intermediate and high-risk types. The low-risk types are HPV6, 11, 42, 43, 44, etc., the intermediate types are HPV31, 33, 35, 39, 51, 52, 53, 55, 58, 59, 63, 68, etc., and the high-risk types are HPV16, 18, 45, 56, etc. The types of HPV-DNA tests carried out clinically have changed from the initial generalized 2 low-risk (6, 11), 2 high-risk (16, 18), and 8 high-risk (16, 18, 31, 33, 45, 52, 56, 58) to the current clearly classified 21 types (6 low-risk: 6, 11, 42, 43, 44, 81 (CP8304); 15 high-risk: 16, 18 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68.; this is of great help to study the disease and analyze the prognosis. Research data show that human papillomavirus (HPV) is a papillomavirus belonging to the family of papillomaviridae, a spherical DNA virus that causes the proliferation of squamous epithelium in the human skin mucosa. It manifests as common warts and genital warts (condyloma acuminata). With the rapid rise in the incidence of warts among STDs and the increase in cervical and anal cancers, human papillomavirus (HPV) infection has become a growing concern.